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Laser Therapy Research for Neuralgia

Low Reactive Level Laser Therapy in the Treatment of Post Herpetic Neuralgia

Katsumi Sasaki, Toshio Ohshiro, Takafumi Ohshiro and Yuki Taniguchi
Laser Therapy. 2010, Vol. 19, No. 2, p.101-105 .

Abstract:Post herpetic neuralgia (PHN) can be an extremely painful condition which in many cases proves resistant to all the accepted forms of treatment. It is frequently most severe in the elderly and may persist for years with no predictable course. Since 1980, we have been applying low reactive level laser therapy (LLLT) for patients with PHN. We report herein on the results of a retrospective study concerning those patients in whom LLLT has been applied for pain attenuation of PHN. One hundred and twenty-three patients (73 male, 50 female, mean age: 66.11yr) have received LLLT for various entities of PHN over the past 29 years. In these cases the affected tissue area(s) was as follows: thorax and back (48 cases); head and neck (41 cases); abdomen and lumbar (17 cases); upper limb (9 cases); and lower limb (8 cases). The overall total improvement rate was 60.16%. Patient whose treatment was given within six month of onset obtained the highest improvement rate (mean, 76.34%). LLLT was effective for PHN in the acute and chronic phase, but LLLT was particularly effective for the acute phase patients whose onset before treatment was 6 months or less. The results demonstrate a significant reduction in PHN pain intensity, hypersensitivity and other complaints

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Laser Therapy for Chronic Pain Syndromes

Osamu Kemmotsu

Abstract:Pain attenuation by laser therapy was evaluated in 441 patients with various kinds of chronic pain syndromes at our clinic with mainly a 60mW CW GaAlAs system operating at 830 nm. There has been found no consistently reliable therapy for neuropathic pain including postherpetic neuralgia. Our clinical data showed 76% patients with postherpetic neuralgia achieved either excellent or good results by laser therapy. Laser therapy is also useful to shorten the pathogenesis of herpes zoster and lower the incidence of postherpetic neuralgia. Laser therapy is a noninvasive, painless and complication-free modality of pain attenuation, and it is safely used even in elderly patients who has cardiovascular and endocrine disorders. Laser therapy has been surely contributing to the improvement of the quality of life and activity of daily life of patients who have painful and debilitating conditions by chronic pain syndromes.

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Double Blind Crossover Trial Of Low Level Laser Therapy In The Treatment Of Post Herpetic Neuralgia

Kevin C Moore Naru Hira. Parswanath S. Kramer, Copparam S. Jayakumar and Toshio Oshiro

Abstract:Post herpetic. neuralgia can he an extremely painful condition which in many cases proves resistant lo all the accepted forms of treatment. II is frequently most severe in the elderly and may persist for years with no predictable course. This trial was designed as a double blind assessment of the efficacy of low level laser therapy in the relief of the pain of post herpetic neuralgia with patients acting as their own controls. Admission to the trial was limited to patients with established post herpetic neuralgia of at least six months duration and who had shown little or no response to conventional methods of treatment. Measurements of pain intensity and distribution were noted over a period of eight treatments in two groups of patients each of which received tour consecutive laser treatments. The results demonstrate a significant reduction in both pain intensity and distribution following a course of low level laser therapy.

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ArneEckerdal and and Lehmann Bastian
Department of Oral and Maxillofacial Surgery and Oral Medicine, Odense University Hospital, Denmark

Abstract:Neurogenic facial pain has been one of the more difficult conditions to treat, but the introduction of laser therapy now permits a residual group of patients hitherto untreatable to achieve a life free from or with less pain. The present investigation was designed as a double-blind, placebo controlled study to determine whether low reactive level laser therapy (LLLT) is effective for the treatment of trigeminal neuralgia. Two groups of patients (14 and 16) were treated with two probes. Neither the patients nor the dental surgeon were aware of which was the laser probe until the investigation had been completed. Each patient was treated weekly for five weeks. The results demonstrate that of 16 patients treated with the laser probe, 10 were free from pain after completing treatment and 2 had noticeably less pain, while in 4 there was little or no change. After a one year follow-up, 6 patients were still entirely free from pain. In the group treated with the placebo system, i.e. the non-laser probe, one was free from pain, 4 had less pain, and the remaining 9 patients had little or no recovery. After one year only one patient was still completely free from pain. The use of analgesics was recorded and the figures confirmed the fact that LLLT is effective in the treatment of trigeminal neuralgia. It is concluded that the present study clearly shows that LLLT treatment, given as described, is an effective method and an excellent supplement to conventional therapies used in the treatment of trigeminal neuralgia.

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Osamu Kemmotsu, Kenichi Sato,Hitoshi Furumido, Koji Harada, Chizuko Takigawa, Shigeo Kaseno, Sho Yokota, Yukari Hanaoka and Takeyasu Yamamura
Department of Anaesthesiology, Hokkaido University School of Medicine, N-15. W-7, Kita-ku. Sapporo 060, Japan.

Abstract:The efficacy of low reactive-level laser therapy (LLLT) for pain attenuation in patients with postherpetic neuralgia (PHN) was evaluated in 63 patients (25 males. 38 females with an average age of 69 years) managed at our pain clinic over the past four years. A double blind assessment of LLLT was also performed in 12 PHN patients. The LLLT system is a gallium aluminum arsenide (GaAlAs) diode laser (830 nm, 60 mW continuous wave). Pain scores (PS) were obtained using a linear analog scale (i) to 10))) before and after LLLT. The immediate effect after the initial LLLT was very good (PS: (}3) in 26, and good (PS: 7-4) in 30 patients. The long-term effect at the end of LLLT (the average number of treatments 36 + 12) resulted in no pain (PS: 0) in 12 patients and slight pain (PS: 1-4) in 46 patients. No complications attributable to LLLT occurred. Although a placebo effect was observed, decreases in pain scores and increases of the body surface temperature by LLLT were significantly greater than those that occurred with the placebo treatment. Our results indicate that LLLT is a useful modality for pain attenuation in PHN patients and because LLLT is a noninvasive, painless and safe method of therapy, it is well acceptable by patients.

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Low reactive-level 830 nm GaAlAs diode laser therapy successfully accelerates regeneration of peripheral nerves in human

Ezekiel Dangwa Midamba and Hans Reidar Haanaes
Department of Oral and Maxillofacial Surgery and Oral Medicine, Odense University Hospital, Denmark
Laser Therapy 5; 125-129, 1993 © John Wiley & Sons, Ltd.

Abstract:Forty patients with short and long-term neurosensory impairment following perioral nerve injuries are presented in this study. Assessment of their sensory level was undertaken using a variety of nerve tests, one of them was a visual analog scale for registration of sensitivity level prior to and after 10 treatment sessions and additionally for 21 of the 40 patients after 20 treatment sessions. Low level laser therapy was applied using GaAlAs 830 nm, 70 mW continuous wave. Dose of 6.0 J/cm2 was standardized for all patients. Improvement of the eight patients with clinical symptoms of less than 1 year after 10 treatments, was between 40-90% and after 20 treatments between 60-80% for the three patients who continued with the treatment. In 32 of the 40 patients with clinical symptoms of more than 1 year in duration, their improvement was estimated at between 40 and 80%, 21 patients completed 20 treatment sessions and the end results were between 60-90%. This was an uncontrolled clinical study of LLLT on perioral nerve injuries and demonstrated the effectiveness of GaAlAs laser on the nerve involved when applied to the nerve trunk and terminal endings. Although controlled research into actual mechanisms and pathways is needed, the preliminary findings are very promising

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